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Cassava Sciences says US DOJ has closed investigation into company

Cassava Sciences says US DOJ has closed investigation into company

ReutersThu, February 19, 2026 at 2:34 PM UTC

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The Department of Justice (DOJ) building in Washington, D.C., U.S., November 28, 2025. REUTERS/Nathan Howard

Feb 19 (Reuters) - Cassava Sciences said on Thursday the U.S. Department of Justice ‌had ended its probe into the ‌company regarding allegations of research misconduct for its ​experimental Alzheimer's drug simufilam.

The company said the probe ended four months after the Justice Department dismissed a criminal indictment in Maryland accusing ‌Hoau-Yan Wang, ⁠a medical professor and former Cassava adviser who allegedly submitted false ⁠data regarding the drug.

Cassava scrapped the development of the drug for Alzheimer's last year ​following disappointing ​clinical trial results.

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The ​biotech has previously been ‌charged by the U.S. Securities and Exchange Commission for misleading claims about the results of Alzheimer's clinical trials. It paid a monetary penalty without admitting to or denying ‌the SEC's allegations.

These outcomes ​end the investigations of ​the company ​by the DOJ and the SEC, ‌Cassava said.

The company is ​now developing ​simufilam for tuberous sclerosis complex-related epilepsy, a rare genetic disorder, according to its ​website.

(Reporting by ‌Jonathan Stempel in New York, Sahil ​Pandey and Sriparna Roy in Bengaluru; ​Editing by Devika Syamnath)

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